This paper reports on the effectiveness and practicality of abstracting essential pedagogical methods that aim to promote high level thinking among junior secondary science students. Strategies include intensive professional development programme and design of lesson materials that can be integrated into the existing science curriculum in the Hong Kong schools. The professional development workshops focus on the distinction between the “Cognitive Skills Enhancing Lessons” (CSE) and regular science lessons. Teachers were stimulated to discuss ways to get students to discuss, think about and respond to teachers’ questions, and to ask questions. Classroom implementations of the CSE teaching materials tailor-made for the Hong Kong junior secondary science curriculum were initiated for 3 secondary two classes. The paper reports on the findings from the pre and post interviews, as well as interviews during the classroom implementations with all the participating teachers and a sample of 6 students from each class. Findings report on what teachers think about the CSE method, their general feelings about using CSE, their comments on the materials, the difficulties (if any) they met, the benefits to students and the perceived feasibility of implementing CSE-infused science activities designed by the project team in local classrooms.