In EFL classroom interaction, discourse markers play a crucial role. This article investigates the use and functions of discourse markers (DMs) in native and local English teachers’ talk in Hong Kong EFL classroom interaction. The 20 most common DMs are examined in this study, and 24 English lessons in the Corpus of English Language Teaching (CELT) developed at the Hong Kong Institute of Education are explored. A comparative study of the use of DMs by local and native English teachers in Hong Kong schools was carried out, and the similarities and differences in DM use are discussed. The findings suggest that there are some similarities but also distinctive differences between the two groups of teachers’ use of DMs. Possible reasons for such differences are explored. The pedagogical implications of the study are discussed at the end of the article.[Copyright © 2015 Center for Promoting Ideas, USA.]