School-based learning community is widely supported by educators as an effective professional development strategy to improve teaching and learning. With reference to the collaborative and supportive features, the professional learning communities (PLCs) are further recognized in schools. Teachers in different schools work collaboratively to solve the actual problems that they come across in their classrooms and improve their teaching practice. With the support of school teachers, education officers and tertiary academics, PLCs was widely adopted as a strategy to enhance teacher professional learning. The tripartite partnership offers a platform for teachers to actively engage in professional sharing about teaching and learning. The paper illustrates the outcome of the lesson study in a two-year project of University-School Support Program (USP). It is evident that the Lesson Study was an effective collaborative mode of professional development for teachers of special schools in Hong Kong.[Copyright © The Hong Kong Special Education Society].