Drawing on data gathered from British Council seminars in Hong Kong, Tokyo and Dubai on Absent Talent: Women in Research and Academic Leadership (2012-2013), this paper discusses academic women's experiences and explanations for women's under-representation as knowledge leaders and producers in the global academy. Participants from South and East Asia, the Middle East, North Africa, Australasia and Europe shared experiences and identified desires for future action in the form of a Manifesto for Change. The paper combines empirical data on enablers, impediments and attractions with consideration of debates on women's exclusions and disqualifications from academic leadership and knowledge production. A key question is whether women are desiring, dismissing or being disqualified from senior leadership positions in the global academy. [Copyright of Higher Education Research & Development is the property of Routledge. Full article may be available at the publisher's website: http://dx.doi.org/10.1080/07294360.2013.864611]